|
You are here: home > gynecologic topics > sexually transmitted diseases
Sexually Transmitted Diseases (STDs)
HIV and AIDS are the most feared of all the sexually transmitted diseases and generally the first to come to mind. The other STDs are more prevalent, though.
In order to prevent any STD it is important to know how they are spread, the common symptoms and how they are treated. STDs affect women and men of all races, backgrounds and economic levels. About 2/3 of these infections are diagnosed in people under the age of 25.
The incidence of STDs is rising. People are likely to have more sexual partners throughout their lifetime than in the past, which increases the risk of STDs. Young people are becoming sexually active earlier, they're getting married later and divorce is more common.
Many STDs have no symptoms, especially in women. These infections can still be spread to sexual partners. Health problems caused by sexually transmitted diseases tend to be more severe for women than men. Some STDs, especially chlamydia and gonorrhea, can spread from the vagina to the uterus and fallopian tubes causing Pelvic Inflammatory Disease (PID). The scarring left by PID can lead to infertility or ectopic pregnancies (a pregnancy outside the uterus which if not terminated early can lead to death.) Human Papilloma Virus, HPV, one of the most common STDs, can cause cervical cancer and other cancers of the genitals. Undiagnosed STDs can be passed from mother to baby before and during delivery. Some infections are easily cured while others may require more extended treatment.
How are STDs Prevented?
- Arm yourself with information. Learn to recognize the symptoms in yourself and your partner.
- Do not have sex if you or your partner have symptoms of an STD and have not seen a health professional.
- Ask your partner about exposure to STDs.
- Use condoms correctly and consistently.
- Have regular checkups for STDs, even in the absence of symptoms.
- Inquire about any available vaccines.
How Do I Know if I am at High Risk for a STD?
- You have had more than one sexual partner in your lifetime
- You know or suspect your partner has had sex with other partners.
- You have shared IV drug needles, or have had sex with someone who has.
- You received blood between 1978 and March of 1985 or have had sex with someone who has.
- You have had an STD in the past.
Get tested if you think you are at risk for a sexually transmitted disease. Any information you share with your physician is confidential. When diagnosed early almost all STDs can be treated effectively, if not cured. It is important to always finish all the treatment prescribed.
Click on link below to go to appropriate category:
Chlamydia
What Is Chlamydia?
Chlamydia is one of the most common sexually transmitted infections in the US, affecting 3-5 million women and men a year. It has been referred to as a "silent epidemic" because the infection has no symptoms in 2/3 of all infected women and half of the infected men. 46% of females with chlamydia are between the ages of 15 and 19 years. Women between the ages of 20 to 24 represent about 33%.
The bacteria that cause chlamydia in the US, chlamydia trachomatis, can infect the mucous membranes in the penis, vagina, cervix, anus, urethra or eye.
Chlamydia can be a serious health threat for women. In women, the infection generally begins on the cervix. An untreated infection can spread to the fallopian tubes or ovaries causing Pelvic Inflammatory Disease (PID). PID can result in sterility by scarring and blocking the fallopian tubes.
In men, chlamydia can cause epididymitis if it spreads from the urethra to the testicles. If epididymitis remains untreated, it can cause sterility in men.
What Are the Symptoms of Chlamydia?
Unfortunately, chlamydia often has no symptoms. Symptoms may begin in as few as five to ten days after exposure.
Symptoms for women may include:
- abnormal vaginal discharge
- bleeding between periods
- vaginal bleeding after intercourse
- abdominal pain
- painful intercourse
- low grade fever
- painful urination
- mucopurulent cervicitis (MPC) - a yellowish discharge from the cervix that may have a foul odor.
Untreated chlamydia can lead to pelvic inflammatory disease. The symptoms of PID include:
- lower abdominal pain
- fever
- vomiting
- abnormal mucus discharge
- longer and/or heavier periods
- increased cramping with periods
- pain during intercourse
- fatigue and weakness
In men the symptoms are similar to the symptoms for gonorrhea. They may appear early in the day and be mild so men may not take them seriously. The symptoms may include:
- pus, watery or milky discharge from the penis
- pain or burning with urination
- redness and swelling in the testicles
In men and women, Chlamydia affecting the rectum can cause itching, bleeding, mucus discharge and diarrhea. Touching the eye with infectious secretions can cause an eye infection characterized by redness, itching and a discharge.
How Is Chlamydia Diagnosed?
In women Chlamydia is diagnosed through examination of the cervix and cervical discharge. A swab taken from the cervix, urethra or anus can be sent to the laboratory for an evaluation.
A Pap test cannot diagnose Chlamydia, but it may indicate that a Chlamydia test would be appropriate.
How Is Chlamydia Treated?
Chlamydia is a treatable infection if treated promptly and appropriately. Chlamydia is treated with antibiotics - most commonly those of the tetracycline or erythromycin families. Both partners must be treated at the same time.
When being treated for chlamydia, remember:
- Take all the prescribed medication. Symptoms may go away before all the bacteria are eradicated from your body.
- Make sure your partner is treated at the same time you are so you do not re-infect each other.
- A follow-up visit is mandatory to test to be sure the bacteria are gone before resuming sexual intercourse.
- Don't share your medicine with anyone.
How Does Chlamydia Affect Pregnancy?
Children born to women with active Chlamydia will be infected 20% to 50% of the time. These infants may develop ear infections, pneumonia and eye infections that can lead to blindness. Ear and respiratory infections in infants caused by Chlamydia are harder to treat than Chlamydia infections in adults.
[return to top]
Gonorrhea
What Is Gonorrhea?
Gonorrhea is a curable sexually transmitted disease caused by the bacterium Neisseria gonorrhea. Gonorrhea is spread through sexual intercourse, whether it is vaginal, oral or anal. Gonorrhea can also be passed to a newborn during delivery.
Gonorrhea is a leading cause of infertility. The most common site of initial infection in women is the cervix and the urethra. If left untreated, the infection can spread to the uterus and fallopian tubes resulting in Pelvic Inflammatory Disease (PID). PID causes scarring of the fallopian tubes, which may lead to infertility or ectopic pregnancy, in which a fertilized egg is implanted outside the uterus, most frequently in the fallopian tube. Ectopic pregnancy can be life threatening.
What Are the Symptoms of Gonorrhea?
The symptoms of gonorrhea usually appear two days to three weeks after exposure to the infection. Unfortunately, you can be infected for months and never know it. Sometimes when symptoms do occur, they are mild.
Symptoms for women may include:
- a vaginal discharge
- painful, burning sensation with urination
- lower abdominal pain and fever
- pain with intercourse
If the symptoms are ignored and the infection goes untreated, the bacteria can spread to the uterus, fallopian tubes and ovaries causing PID. PID causes scarring that can lead to infertility or ectopic pregnancies.
Symptoms for men may include:
- painful burning sensation with urination
- milky white to yellow discharge from the penis
- redness and swelling around the opening of the penis
- pain and swelling in the testicles
How Is Gonorrhea Diagnosed?
Gonorrhea is diagnosed from a DNA test using swab specimens from the cervix, rectum, throat or urethra.
How Is Gonorrhea Treated?
Gonorrhea can be cured by antibiotics. It is important to complete all the medication, even if you have no symptoms or your symptoms go away. All partners must be treated at the same time. You should abstain from intercourse until you and your partner have completed the course of medication and both have obtained a negative result from a repeat culture.
How Does Gonorrhea Affect Pregnancy?
Pregnant women with gonorrhea are at increased risk of premature delivery. Untreated gonorrhea can be transmitted to the infant during birth and may cause severe eye infections.
[return to top]
Genital Herpes
What Is Genital Herpes?
Genital herpes is a contagious viral infection that is most often acquired through sexual contact. The viruses that cause genital herpes are related to the group of viruses that include chicken pox and mononucleosis. Herpes Simplex Virus 1 (HSV1) most commonly causes sores around the mouth while Herpes Simplex Virus 2 (HSV2) is associated with sores on the genitals. However, either virus can cause sores around the mouth or on the genitals.
It is estimated that 45 million Americans have the HSV virus; this is one of every four Americans. As many as 75% of the people infected with genital herpes may not exhibit symptoms, however they can still pass the infection to their sexual partners.
Herpes is passed through skin-to-skin contact with someone who is infected. This generally occurs during sexual activity. HSV can be introduced to the genital area through oral sex. About 20% of the new outbreaks of genital herpes are the result of oral sex.
The virus does not survive long outside the human body. Therefore, the virus is spread rarely, if ever, through contact with bath towels, toilet seats or hot tubs.
The severity and length of herpes outbreaks varies from person to person. The outbreaks usually become less frequent over time.
What Are the Symptoms of Genital Herpes?
The classic symptom of a genital herpes outbreak is a cluster of painful ulcers on the labia and/or buttocks. However, as many as 2/3 of all men and women infected with herpes never have any symptoms, or have mild symptoms which they mistake for a rash or mosquito bite. The remaining 1/3 are not so lucky.
About 2 to 10 days after the herpes virus enters the body, flu-like symptoms may appear. These include swollen glands, fever, chills, muscle aches, fatigue and nausea. Additionally, ulcers that began as small red bumps change to painful fluid-filled blisters. These blisters rupture then ooze and bleed. After 3-4 days scabs form and the ulcers heal without scarring. The first episode usually lasts from 2 to 3 weeks.
After the initial outbreak heals, the virus remains in the body, hiding in the nerves at the base of the spinal cord in an inactive state. Periodically it can travel through the nerves to the skin at or near the site of the original outbreak. Once on the skin, the virus multiples and new sores erupt. The virus can also reactivate with no outward signs, infecting a sexual partner.
The recurrent episodes are generally milder than the initial outbreak and usually last about a week. Often there is a warning symptom, called a prodrome, that signals an outbreak. These warning symptoms may include a tingling sensation or itching at the site of infection, pain in the buttocks or down a leg. Sometimes only the prodrome appears with no visible sores or with very small, barely visible blisters. At other times open sores may develop, crust over and then go away.
Some people may recognize only one to two outbreaks in their lifetime; others may have several outbreaks a year. The number and pattern of outbreaks usually change over time. Researchers do not yet understand why some people have many outbreaks, or why others have so few. They do not yet know what makes the virus reactivate. It is thought the reoccurrences can be brought on by physical or emotional stress, menstruation or immunosuppression.
How Is Genital Herpes Diagnosed?
The most common methods used to diagnose genital herpes are a viral culture and a test for viral DNA. For either test, a swab of fluid is taken from an active lesion. The tests must be performed before the ulcers scab over.
A negative test result does not necessarily mean that herpes is not present. If the lesion clinically appears to be genital herpes, caution should be taken as though the test was positive. If another outbreak occurs, the ulcers should be tested at the earliest sign.
There are blood tests available to test for the presence of HSV-1 and HSV-2 antibodies. Because the body makes antibodies in response to infection, the blood test may not be positive until several weeks after exposure. The blood test is also not site specific, therefore, especially in the case of HSV-1, the test may be picking up cold sores.
How Is Genital Herpes Treated?
Although there is no cure for herpes, there are several prescription medications that can reduce the severity of the symptoms and decrease the length of the outbreak. These medications interfere with the ability of the virus to reproduce. The medications work best if taken at the first sign of an outbreak, during the prodrome.
People with recurrent infections (6 or more per year), or who will be delivering a baby soon, may want to take medication daily to help prevent outbreaks.
Any time there is an active herpes outbreak it is important to follow a few simple rules to help speed healing and prevent transferring the infection to other sites on the body (self inoculation) or to other people.
- Keep the area clean and dry to prevent a secondary infection. A portable blow dryer can be used to dry the area after a shower or bath. Panties with a cotton crotch should be worn to allow air to circulate.
- Avoid touching the sores and wash your hands after any contact with the sores.
- Avoid sexual contact from the time the symptoms first are recognized until the sores are completely healed.
How Does Herpes Affect Pregnancy?
All women who are pregnant should tell their physician if she or her partner has a history of herpes. During pregnancy the initial or recurrent infections can be more severe.
Babies born to women during an HSV outbreak may become infected. Most infants who are infected came into contact with the virus as they passed through the birth canal. Infants who are infected with the herpes virus can have serious skin infections, damage to the nervous system, blindness, mental retardation or death.
The risk to the newborn is the highest if the infant is delivered during the mother's primary outbreak. Usually if there are no active sores at the time of labor the baby can be delivered vaginally. If there is an active infection, a Cesarean section may be recommended.
Medication such as acyclovir is usually given during the last month of pregnancy to prevent an outbreak close to delivery.
[return to top]
Syphilis
What Is Syphilis?
Syphilis is a sexually transmitted disease caused by small spiral-shaped bacteria called Treponema pallidum. Syphilis once caused devastating epidemics, but it can now be easily diagnosed by a blood test and effectively treated with antibiotics.
Syphilis is spread through sexual or skin-to-skin contact with someone who is in an infectious stage when the symptoms are present. Syphilis spreads through open sores or rashes containing bacteria that can penetrate the mucous membranes of the genitals, mouth or anus. Because the bacterium is very fragile, the infection is almost always spread by sexual contact.
Syphilis occurs in stages. The disease is more easily spread in some stages than in others.
What Are the Symptoms of Syphilis?
Once the bacteria enter the body, the disease may progress through four stages depending on when the treatment is initiated. Left untreated, syphilis can cause blindness, insanity, paralysis, heart disease or death. Symptoms can appear within 10 to 90 days following exposure. The symptoms of syphilis are divided into four stages.
1) Primary Stage
The first sign of syphilis is usually a painless ulcer called a chancre. The chancre may look like a pimple, blister or an open sore. The chancre makes its appearance usually at or near the place where the bacteria entered the body. The chancre may occur inside the body where it will go unnoticed. Only about 10% of the women who develop chancres notice them. The disease is highly contagious during this stage. With or without treatment, the sore will heal (usually within 1 to 5 weeks) but the bacteria within the body will continue to increase and spread. About 1/3 of the people infected will progress to chronic stages.
2) Secondary Syphilis
About 2 weeks to 6 months after the chancre is gone a rash appears consisting of brown sores about the size of a penny. The rash is almost always on the palms of the hands and soles of the feet, but could also appear on other parts of the body. At this stage any physical contact, sexual or nonsexual, with the broken skin of the infected person may spread the disease. The rash usually heals within several weeks to months. Other symptoms that may occur include mild fever, fatigue, headaches, sore throat, swollen lymph glands, loss of appetite, hair loss and muscle, joint or bone pain. The symptoms tend to be mild, may come and go over the next one to two years, and will disappear without treatment.
3) Latent Stage
During this stage the disease is not contagious and there are no symptoms. This stage may last many years. Many people who are not treated will have no further evidence of the disease. Approximately 1/3 of those who have secondary syphilis will go on to develop tertiary syphilis.
4) Tertiary Syphilis
During this stage the bacteria will cause damage to the almost any part of the body, particularly the heart, eyes, brain, nervous system, bones and joints. There can be symptoms such as slurred speech, paralysis, insanity or senility. If left untreated, tertiary syphilis can cause death. This stage can last for years, even decades. This is not an infectious stage.
What Is Neurosyphilis?
The syphilis bacteria frequently invade the nervous system during the early stages of syphilis. Approximately 3% to 7% of untreated persons with syphilis will develop neurosyphilis during the early stages of syphilis. Symptoms may include headache, stiff neck and fever due to the inflammation of the lining of the brain. Some people develop seizures. If the blood vessels are affected, symptoms of a stroke may develop with numbness, weakness or visual complaints. The time from infection to developing neurosyphilis can be as long as 20 years. The course of neurosyphilis and the treatment may be different with patients with HIV infection.
How Is Syphilis Diagnosed?
There are three ways to diagnose syphilis. A physical exam may reveal the presence of an infection. Secondly, the syphilis bacteria collected from a surface scraping of an ulcer or chancre can be identified using a microscope. Finally, a blood test is the most common way to diagnose syphilis. Some other medical conditions may result in a false negative or false positive result. These can be discussed with your physician.
How Is Syphyilis Treated?
Syphilis is usually treated with penicillin given by injection. There are other antibiotics that can be used in patients who are allergic to penicillin. Because some people do not respond to the usual dose of penicillin it is important to have follow up blood tests. Those with neurosyphilis may need to be tested for up to two years following treatment.
The disease usually becomes non-infectious 24 hours after beginning therapy.
Antibiotics can cure syphilis in all stages. However, once the disease reaches the tertiary syphilis stage, organ damage is irreversible.
How Does Syphilis Affect Pregnant Women?
Syphilis infects the fetus after 16-18 weeks gestation. If infection occurs during pregnancy, neonatal death or stillbirth occurs about 25% of the time.
Some infants with syphilis display symptoms at birth, but most will develop symptoms between 2 weeks and 3 months later. The symptoms may include: skin sores, rashes, fever, weakened or hoarse crying sounds, swollen liver and spleen, jaundice (yellow skin and whites of the eyes), anemia and birth defects. If the infant is not treated early, blindness, brain damage and problems with growth and development may appear. As the child grow older and becomes a teenager they may develop late-stage syphilis including damage to their bones, teeth, eyes, ears and brain.
[return to top]
Hepatitis
What Is Hepatitis?
Hepatitis is an inflammation of the liver. It can be caused by viruses or other factors, including alcohol abuse, certain medications or physical trauma. Some cases of hepatitis are not a serious threat to health, but the disease can become chronic and can lead to liver failure and death.
There are four major types of viral hepatitis:
- Hepatitis A - The infection caused by the hepatitis A virus is usually mild and does not become chronic. The virus is most commonly spread by food and water contamination, although it can be passed through sexual practices involving oral-anal contact.
- Hepatitis B - The infection caused by the hepatitis B virus (HBV) is most often passed to a sexual partner during sexual intercourse, especially during anal sex. HBV can also be passed through contact with infected blood, such as with shared needles or a needle stick with contaminated blood, or from a mother to her newborn. The infection may be mild, severe acute or chronic.
- Non-A, Non-B - This infection is primarily caused by the Hepatitis C virus (HCV). The infection is usually mild, but is more likely than HBV to lead to chronic liver disease. With new blood donor screening tests, the likelihood of being infected with HCV has diminished. It is now most often contacted through shared needles or an accidental needle stick in a health care setting. However, it can be spread sexually.
- Hepatitis E - This is another type of non-A, non-B hepatitis. The virus is usually found in areas with poor sanitation. It has not been found in the US and is not spread through sexual contact.
- Delta Hepatitis - The hepatitis D virus (HDV) only produces disease when HBV is present. Most cases have occurred in people who are frequently exposed to blood or blood products, such as hemophiliacs, or among drug users sharing contaminated needles.
How Is Hepatitis Spread?
HBV, HCV and HDV are spread in the following ways:
- Through sexual intercourse with a contaminated person without the use of a condom.
- Sharing contaminated needles among users of injected street drugs.
- Needle stick accidents in a health care setting.
- Mother to child transmission of HBV during birth.
- Transfusions of blood or blood products. Until recently blood transfusions were the most frequent cause of hepatitis C. Blood banks in the US now routinely screen donated blood for HBV and HCV. Tests for HBV also screen out HDV. The risk of acquiring hepatitis through a blood transfusion is very low.
- Personal contact with an infected person. It is spread by contact with virus-infected blood or body fluids, usually through cuts and scrapes or semen (sexual intercourse without a condom) or by sharing personal items such as razor or toothbrush.
What Are the Symptoms of Hepatitis?
The most common early symptoms are mild fever, headache, muscle aches, fatigue, loss of appetite, nausea, vomiting or diarrhea. Later symptoms may include dark and foamy urine and pale feces, abdominal pain, and jaundice (yellowing of the skin and the whites of the eyes). However, 40% of those who have been infected with viral hepatitis have no symptoms. When symptoms are present they can range from mild to severe.
Many of those with HBV only develop flu-like symptoms. Some patients with a more severe form of hepatitis B may develop short-term arthritis-like symptoms. Very severe HBV is rare but can be life-threatening. Early signs, including personality changes and agitated behavior, require immediate medical attention.
Some people, who are infected with HBV or HCV but have no symptoms, become chronic carriers. There are an estimated 1.5 million HBV carriers in the US (300 million carriers worldwide.) About 90% of the babies infected at birth with HBV become chronic carriers. At least ½ of all HCV carriers, whether or not they had symptoms, go on to develop chronic liver disease.
How Is Hepatitis Diagnosed?
Several blood tests can detect HBV, HCV or HDV even before symptoms develop. A number of blood tests can also be performed to determine how well the liver is functioning.
How Is Hepatitis Treated?
The acute symptoms of viral hepatitis are usually treated by bed rest, a healthy diet and no alcoholic beverages. Antibiotics are not used to treat hepatitis.
The drug interferon alpha may be used to treat chronic HBV and HCV. Interferon alpha is a genetically engineered form of a naturally occurring protein. The drug improves liver function and may decrease symptoms, although interferon alpha has its own side effects, such as headache, fever and flu-like symptoms. Not all patients respond to interferon alpha. For other patients the benefits may decrease over time.
How Does Hepatitis Affect Pregnant Women?
HBV can be transmitted during childbirth. It is recommended that pregnant women receive a blood test to see if they are a chronic carrier of HBV. If a woman tests positive for HBV, the baby can receive hepatitis B immune globulin and a vaccination for HBV immediately after birth. Immune globulin offers temporary protection and the vaccine provides a longer lasting immunity.
[return to top]
Molluscum Contagiosum
What Is Molluscum Contagiosum?
Molluscum contagiosum is a benign viral infection of the skin caused by the pox virus. Molluscum contagiosum most often affects young children who pass it to each other through saliva while in adults the virus is sexually transmitted. Molluscum is spread by direct contact with infected skin and can be spread to various parts of your body and to other people.
The lesions are usually on the genitals, lower abdomen, buttocks or inner thighs. The rash caused by molluscum contagiosum causes painless wart-like bumps.. The rash usually develops 2 to 7 weeks after exposure.
What Are the Symptom of Molluscum Contagiosum?
Molluscum causes normal skin to grow into bumps. There is no pain or discharge associated with the bumps unless they are accidentally cut.
How Is Molluscum Contagiosum Diagnosed?
Your physician can diagnosis molluscum contagiosum by observation.
How Is Molluscum Contagiosum Treated?
Molluscum contagiosum is treated by excising the lesions.
[return to top]
Pubic Lice, Crabs
What Are Pubic Lice or Crabs?
Public lice, or crabs, is the common name for Pediculosis. Pediculosis is a tiny crab-like parasite that is usually found in the pubic hair of infected men and women, and occasionally in the hair of the chest, armpits, eyelashes and eyebrows.
Usually the parasites are spread through personal contact, although in a few cases they have been picked up through contact with infected bedding or clothing.
What Are the Symptoms of Pubic Lice or Crabs?
The main symptom is severe itching in the genital or other affected area. Scratching can transfer the lice to uninfected parts of the body.
How Is Pubic Lice Diagnosed?
Diagnosis is easy because the lice are visible to the naked eye. They are the size of the head of a pin, oval and grayish, but appear reddish-brown when full of blood from their host. The nits, or tiny white eggs, are also visible clinging to the base of the pubic hair.
How Is Pubic Lice Treated?
Lotions and shampoos that kill pubic lice are available both over the counter and by prescription. Pregnant women should not use the over the counter products and should call their physician for advice.
None of the drugs should be used in or around the eyes. An ophthalmic petroleum jelly should be used for lice in the eyebrows.
All persons who also may be infected due to intimate contact should be treated.
All clothing and bedding should be dry-cleaned or washed in very hot water (125 degrees F), dried at a high setting and ironed to rid them of any lice or nits. Pubic lice die within 24 hours of being separated from the body while the eggs may live up to six days.
[return to top]
Human Papilloma Virus and Condyloma (Venereal Warts)
HPV, or Human Papilloma Virus, may well be the STD of the new millennium. The virus has been studied for a relatively short time but already 80 different genotypes have been identified in the US. Approximately 20 to 30 are known to infect the genital area. Even though the viruses are not a reportable disease, it is believed that 75% of reproductive-age adults are infected with one or more types of the virus, with an estimated 5.5 million new cases a year.
The virus was named "Papilloma virus" because they are known to cause warts, or papillomas. The strains of HPV that cause warts on the hands and feet are different from the strains that cause genital warts. Not all the viruses, though, cause warts. Sometimes the virus lives on the skin without showing any symptoms. Many people with HPV are not aware they are infected.
There are strains of HPV that can cause cancers of the vulva or cervix in women, the penis in men or the anus in men and women.
The HPV types that are responsible for genital infections have been divided between "low risk" and "high risk" types, depending upon whether the virus type is associated with genital cancer.
HPV is usually transmitted by sexual contact. The time period between the exposure to the virus and any manifestation of symptoms is unknown. It can be anywhere from several weeks to years making it difficult to know exactly when a person is infected.
Condoms can help avoidance with the virus, but do not prevent it. The only parts of the genitals protected are those covered with latex.
What Are the Symptoms of Human Papilloma Virus?
The HPV types that are associated with genital infection are divided into two types - low risk and high risk, depending upon whether they are associated with genital cancers. Low risk HPV is usually associated with genital warts (also known as condyloma accuminata or venereal warts.) Genital warts are small pink or red bumps on the vulva, vagina, cervix penis shaft, urinary opening or anus. Generally they are painless, but there may be burning or bleeding when irritated. Genital warts tend to occur in clusters. They may grow into a cauliflower-like growth.
High risk HPV has been linked to various cancers in both women and men. Nearly all cases of cervical cancer are caused by a high risk HPV virus. These infections can not be seen with the naked eye.
How Is Human Papilloma Virus Diagnosed?
The diagnosis of genital warts is usually made by a healthcare professional who simply looks at the area. If there is a question the wart may be removed and sent to a pathologist at a lab for diagnosis.
Often HPV infection may first be suspected after an abnormal pap smear. On the basis of the abnormal pap, a colposcopy may be recommended. During this exam, a health care professional will apply acetic acid to the cervix to help identify HPV infection otherwise invisible to the eye. The solution causes "aceto-white patches" which are especially visible with the use of a colposcope. A colposcope is an instrument that looks like binoculars on a stand that is used to inspect the infected area under magnification. A biopsy may be taken to aid in the diagnosis.
There is a test available to detect the HPV DNA. The swab is taken of the vagina or cervix and sent to a laboratory. The test only indicates whether the virus is being shed at the place and during the time the test is performed. A negative test does not necessarily mean exposure to the virus has not taken place. The result of the DNA test indicates whether the viral DNA detected is low risk type or high risk.
What Is the Treatment for Human Papilloma Virus?
As with other viruses, there is no cure for HPV. Genital warts may come and go on their own, or may persist despite aggressive treatment. Treatment of genital warts is easiest when the warts are small and few in numbers.
None of the treatments discussed below will guarantee that the warts won't return and all treatments cause a local irritation. The goal with treatment of genital warts is to remove visible warts and annoying symptoms.
Treatments that are applied by a health care professional include:
- TCA (trichloracetic acid) is a chemical painted on the surface of the wart to destroy it. The acid may cause some localized burning as it dries. It takes weekly treatments for a number of weeks to get rid of the warts - they should turn white, shrink and disappear.
- Podophyllin is another chemical that can be painted on condyloma. It also causes burning as it dries and should be washed off with soap and water 4 to 6 hours after application.
- Other methods used to treat genital warts are cryotherapy (freezing the warts off) and laser therapy (burning the warts off with a beam of light).
There are a few new products that have been introduced that can treat the warts at home:
- Podofilox (Condylox) solution or gel can be applied at home twice a day for 3 days, followed by 4 days of no therapy. This regiment can be repeated up to four times.
- Imiquimod (Aldara) stimulates the immune system to target the warts. The cream is applied three times a week for up to 16 weeks.
How Does Human Papilloma Affect Pregnancy?
Genital warts can cause problems during pregnancy. Sometimes they enlarge, causing difficulty with urination. Warts on the wall of the vagina can cause obstruction with delivery.
There are safe ways to treat genital warts during pregnancy.
[return to top]
HIV and AIDS
AIDS (acquired immunodeficiency syndrome) is the most severe form of HIV (human immunodeficiency virus). AIDS was first reported in 1981 and is now a worldwide epidemic. HIV progressively destroys the cells of the immune system thereby damaging the body's ability to fight off viruses, bacteria and fungus that cause disease. Opportunistic infections, such as pneumonia, meningitis and certain types of cancers, can develop in people with HIV and AIDS. The microbes that cause infections generally wouldn't cause illness in a healthy person; but for a person with a weakened immune system the infections can be life threatening.
An estimated 1 million Americans are currently living with HIV. During the last fifteen years HIV infection among women has dramatically increased. In 1992 women made up 13 % of people with AIDS; in 2007, 38% of the people living with AIDS were women. AIDS is the fifth leading cause of death for women in the US ages 25 to 44. For African-American women in this age group, AIDS is the third leading cause of death.
How Is HIV Spread?
HIV is transmitted through the blood, semen or vaginal secretions of an infected person. HIV is usually spread by sexual contact with an infected person. It can also spread through sharing contaminated needles or syringes among drug users. Untreated women can pass the infection to their children during pregnancy, birth or through their breast milk.
Although HIV has been found in the saliva of infected people, no evidence exists that the virus is passed through saliva. Saliva appears to have natural compounds that inhibit the infectiousness of HIV. Researchers have found no evidence that HIV is spread through urine, feces, sweat or tears. HIV is not passed through casual contact, such as through insect bites or stings.
The risk of acquiring HIV from an infected health care worker is extremely low. There have been only two documented cases of an HIV-positive surgeon transmitting the virus to a patient.
Having another sexually transmitted disease such as herpes, gonorrhea, chlamydia or syphilis may make a person more susceptible to acquiring the virus through unprotected sex with an infected person.
What Are the Symptoms of HIV?
Fever, malaise and enlarged lymph nodes are the most common symptoms of HIV/AIDS. However, many people don't develop symptoms when they are first infected with HIV. Some people, though, develop a flu-like illness within a month or two of exposure to the virus. The symptoms usually disappear within a week to a month and are commonly mistaken for other viral illnesses. People are very infectious during this period.
More severe symptoms may not appear for more than a decade after the virus enters the body. During this asymptomatic period, the virus is actively multiplying, infecting and killing cells of the immune system. The virus disables or destroys the T4 cells (or CD4+T cells), which are the immune system's key infection fighters.
As the immune system deteriorates, complications begin to surface. One of the first symptoms to appear is swollen glands, or enlarged lymph nodes, that remain swollen for longer than three months. Other symptoms that may begin to appear include fatigue, weight loss, frequent fevers and sweats, frequent yeast infections (vaginal and oral), persistent skin rashes, short term memory loss or flaky skin and Pelvic Inflammatory Disease (PID) that doesn't respond to medication. Some people develop severe herpes sores in the mouth, genitals or anus.
What Are the Symptoms of AIDS?
The most advanced stage of HIV infection is known as AIDS. In 1993 the CDC revised the definition of AIDS, to include all HIV infected people who have fewer than 200 T4 cells (healthy adults usually have 1,000 or more.) The definition also includes 25 conditions, mostly opportunistic infections that affect people with advanced HIV disease. Opportunistic infections
develop when the immune system can no longer fight off certain bacteria, viruses and other microbes. The infections can cause such symptoms as coughing, shortness of breath, seizures, mental confusion and forgetfulness, severe and persistent diarrhea, fever, vision loss, severe headaches, weight loss, extreme fatigue, nausea, vomiting, lack of coordination, coma, abdominal cramps, or difficult or painful swallowing.
People with AIDS are particularly prone to various cancers caused by viruses, such as Karposi's sarcoma, cervical cancer and lymphomas. These cancers are harder to treat and usually are more aggressive in people with AIDS.
How Is HIV Diagnosed?
The first tests for HIV antibodies were developed to screen donated blood and were then expanded to test people at risk for HIV infection. There are two standard tests for HIV.
First is the Enzyme Linked Immunosorbent Assay (ELISA) test. EIA detects the antibodies that are produced in response to HIV infection. A second test, the western Blot test, is a more specific test that can differentiate between HIV antibodies and other antibodies that can react to the EIA. If the EIA test result is positive, it will be repeated using the same blood sample. If the second EIA test is also positive, a Western Blot test will be performed on the same blood sample.
HIV antibodies usually do not reach detectable levels until 1 to 3 months following infection. It can take as long as 6 months to have enough antibodies created in large enough quantities to show up in standard blood tests.
People who think they have been exposed to HIV should be tested for HIV as soon as they are likely to have developed antibodies. Early testing allows treatment to begin at a time when they are most able to combat HIV and prevent opportunistic infections.
How Is HIV Treated?
The treatment for HIV has been rapidly evolving. The earlier HIV is detected the sooner treatment can be started. The initial viral surge can be decreased if treatment is initiated soon after the HIV infection. The drugs can delay the gradual weakening of the immune system. The treatment may also reduce the chance of spreading the disease to a partner. The treatments not only decrease the amount of virus in the blood, but also in the bodily fluids.
One group of drugs used to treat HIV infection are called nucleoside analog reverse transcriptase inhibitors (NRTIs), The most well known of these drugs is AZT. They work by interrupting an early stage of virus replication. These drugs may slow the spread of HIV in the body and delay the onset of opportunistic infections. However, these medications do not prevent the spread of HIV to others.
A second group of drugs, non-nucleoside reverse transcriptase inhibitors (NNRTIs), also inhibit viral replication.
The third group of drugs, protease inhibitors, interrupts the virus from making copies of itself once the virus has entered a cell.
These drugs do have side effects that can be serious. AZT can cause a decrease in red or white blood cells in the blood, especially in the later stages of the disease. The protease inhibitors can cause nausea, diarrhea and other GI symptoms. These can also cause an abnormal distribution of body fat, especially paunches or bumps.
In 1996 a new test, called the viral load test, was introduced to monitor how well the body is responding to treatment. The viral load test measures the amount of HIV in the blood in terms of "copies per milliliter." A high normal load indicates the person is progressing towards AIDS, while a low viral load indicates the immune system is keeping the infection in check.
Women can transmit the HIV virus to their babies during pregnancy, birth or through breastfeeding. One fourth to one third of all untreated women will pass the infection on to their babies. If the drug AZT is taken during pregnancy the risk of passing the virus to the child is reduced by two thirds. If AZT is used along with delivering the baby by cesarean section the infection rate is dropped to 1%. Women infected with the HIV virus should not breastfeed their babies.
How Does HIV/AIDS Affect Pregnancy?
Women can transmit the HIV virus to their babies during pregnancy, birth or through breastfeeding. One fourth to one third of all untreated women will pass the infection on to their babies.
Taking the drug AZT during pregnancy reduces the risk of passing the virus to the infant by two-thirds. .If AZT is used along with delivering the baby by cesarean section the infection rate is 1%.
Women infected with the HIV virus should not breastfeed their babies.
[ return to top ]
meet our physicians ::
our locations ::
obstetric topics ::
gynecologic topics
office procedures and policies ::
hospitals ::
insurance and billing
our mission statement ::
homepage ::
patient forms
© Mt. Auburn Obstetrics and Gynecologic Associates, Inc.
|